Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma with marked biologic heterogeneity.We analyzed 100 cases of DLBCL to evaluate the prognostic value of immunohistochemical markers derived from the gene expression profiling-defined cell origin signature, including MYC, BCL2, BCL6, and FOXP1 protein expression.We also invest
Fully grouted bolts are a key component of the support system for underground openings.Although considerable effort has been made in the simulation of the reinforcement effect of the fully grouted bolts on the rock masses surrounding underground openings, most of the work has limited significance since the structural element approach is used.This s
Erect-crested penguins are the least studied of all penguins.They breed on two isolated subantarctic island groups, the Antipodes and Bounty Islands.Sporadic nest counts indicate a dramatic decline in numbers of erect-crested penguins over the last 50 years.Here we present data from a study undertaken in 1998 on the breeding biology, behavior and h
Abstract Background Increasing evidence suggests a critical role for long noncoding RNAs (LncRNAs) and pseudogenes in cancer.Renal cell carcinoma (RCC), the most common primary renal neoplasm, is highly aggressive and difficult to treat because of its resistance to chemotherapy and radiotherapy.Despite many identified LncRNAs and pseudogenes, few h
As a traditional rice wine, sweet fermented rice (SFR) is widely loved because of its unique flavor and high nutritional value.However, the physicochemical properties, microbial community composition, and metabolic pathway changes during the fermentation process of sweet wine have not been evaluated, and these changes can lead to unstable SFR quali